Best Hospitals to Work For in South Carolina
🏥 Top Hospitals to Work For in South Carolina (2025 Edition)
South Carolina continues to attract healthcare professionals from across the country, thanks to its lower cost of living, family-friendly communities, and growing job market. From the beaches of Charleston to the upstate tech corridor in Greenville, this is a state where nurses, allied health workers, and physicians can build fulfilling careers.
What makes it even more appealing for clinicians? Several of South Carolina’s hospitals are recognized nationally for excellence in patient care, nursing outcomes, and innovation. Many have earned Magnet status from the American Nurses Credentialing Center (ANCC), and some have been ranked among the nation's best by U.S. News & World Report.
Here are some of the top hospitals in South Carolina for healthcare professionals in 2025:
🔝 MUSC Health – University Medical Center (Charleston)
- #1 hospital in South Carolina, according to U.S. News
- Magnet recognized
- Nationally ranked in ENT, OB-GYN, cancer care, and more
- Academic teaching hospital and research leader
MUSC Health continues to set the benchmark for excellence in both care delivery and clinician experience. With a massive expansion underway, including new outpatient sites and a virtual care network, it's a standout employer for clinicians who want access to cutting-edge tools and a strong mission-driven culture.
💼 Lexington Medical Center (West Columbia)
- First hospital in SC to receive Magnet with Distinction
- High-performing in heart failure, stroke, and joint replacement
- Known for its collaborative nurse leadership and mentorship programs
Lexington Medical Center has become one of the most sought-after employers for nurses in the Midlands region. It consistently earns high marks from staff for its investment in professional growth, leadership development, and team culture.
🏥 Prisma Health – Greenville Memorial Hospital
- South Carolina's largest nonprofit health system
- Offers Level I trauma care and a large children’s hospital
- Major teaching affiliate of the University of South Carolina School of Medicine Greenville
Prisma Health’s upstate facilities are deeply integrated into the region’s education and innovation ecosystem. Clinicians here often participate in research, mentorship, and multidisciplinary projects while working with diverse patient populations.
🌿 Roper St. Francis Healthcare (Charleston)
- Includes Roper Hospital, Bon Secours St. Francis Hospital, and Mount Pleasant Hospital
- Recognized for patient experience, orthopedic surgery, and cardiology
- Faith-based, community-centered approach
The Roper St. Francis system combines the personal feel of a community hospital with the scale and stability of a larger health network. It's a favorite among nurses seeking balanced schedules and supportive leadership.
❤️ Why These Hospitals Stand Out
- Magnet Designation: A proven marker of nursing excellence, professional development, and nurse-led innovation.
- Top Patient Safety Scores: Many of these facilities have received “A” grades from The Leapfrog Group.
- Supportive Environments: Glassdoor and Indeed reviews consistently praise leadership transparency, work-life balance, and team collaboration.
- Career Growth: Structured clinical ladders, tuition support, and specialty certification programs are common benefits.
📈 Looking to Work at One of These Facilities?
Here’s how to stand out:
- Keep your resume and licensure documents current.
- Start a free profile on Goodwork to be matched directly with facilities hiring for your skillset.
- Consider connecting with South Carolina Nurses Association or local alumni networks for referral opportunities.
Whether you're just starting your career or seeking your next big step, South Carolina offers more than just sunshine and charm, it’s a place where healthcare workers are valued, supported, and given room to grow.
🔗 Ready to explore openings at top South Carolina hospitals?
Start here: https://goodwork.world/explore-jobs